
Tony Edge explains how SPE optimization improves oligonucleotide LC–MS data.
Dr. Tony Edge is President of the UK Chromatography Society, supporting the next generation of scientists to develop their skills. Prior to this he was a business analyst at TetraScience, helping scientists liberate, unify and transform raw data into more-than-FAIR, AI-native data, bringing AI-native data to life in a rapidly growing suite of next-generation lab data management solutions, scientific use cases and AI-based scientific outcomes. He has also worked as the R&D Manager at Avantor, heading a team of specialist scientists in developing next-generation stationary phases for HPLC. He has worked in both manufacturing and industry, having periods of employment at LGC and AstraZeneca as well as Thermo Fisher Scientific and latterly Agilent Technologies. In 2008, he was fortunate enough to be awarded the Desty Memorial Lecture for his contributions to innovating separation science, and in the same year also won a clinical excellence award from AstraZeneca. He is also a member of the permanent scientific committee for the International Symposium on Chromatography.

Tony Edge explains how SPE optimization improves oligonucleotide LC–MS data.

A worrying trend has emerged in UK higher education: the systematic erosion of deep, hands-on chromatography instruction and delivery of this key technique by non-experts, according to Tony Edge, President of The Chromatographic Society (ChromSoc). Can this trend be reversed?

This article explores the current applications of artificial intelligence (AI) in chromatography. It anticipates AI’s transformative benefits for the future, looking at the impacts that separation scientists will inevitably see and are already seeing.

This year, the ISC’s theme is “Imagine a world of Chromatography." Here, we will see conference attendees discuss a wide variety of disciplines where chromatography plays a crucial role.

Governments are striving to implement policy changes towards a greater use of green technology, specifically around the generation of energy. Individuals and industrial organizations have also taken up the challenge, and now many companies are driving to significantly reduce their environmental footprint, or indeed become carbon negative within very short time frames.

What is the state of separation science in UK and what steps can be taken to promote the importance of the subject?

Sustainability concerns are renewing interest in SFC, often as a substitute for HPLC. With the broader application of SFC, we need a better understanding of selectivity in SFC, where stationary phase classification is not well established. This study assessed and measured the selectivity differences afforded by three prototype SFC phases.

This article discusses the development of a series of applications that will allow for the determination of a number of nitrosamines that have been identified by the FDA as genotoxins to monitor, initially showing how to perform a separation of these compounds from the API and then looking at how MS can be applied to the analysis to ensure that the required detection limits can be reached.

Special Issues
The Reid International Bioanalytical Forum is a conference geared towards bioanalytical scientists. It has a unique philosophy where challenging data is often presented to an audience who are encouraged to engage. This article describes how the meeting series was initiated and developed over the past 40 years and how this philosophy has been embedded into the meeting.

Special Issues
A theme for The Chromatographic Society Diamond Jubilee Year is to increase public awareness of chromatography. Often the general public, and even chromatographers themselves, fail to appreciate the importance of chromatography. Here Tony Edge, The Chromatographic Society Vice-President, discusses just how much chromatography underpins everyday life.

LCGC North America
Turbulent flow chromatography is often used for on-line sample cleanup of biological matrices in liquid chromatography–mass spectrometry applications.

June 1st 2022

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