In Part 2 of "Conversations with Michael Dong," the LCGC column editor discusses HPLC columns for pharmaceutical analysis and the case for short columns.
|Articles|March 26, 2014
LCGC TV: The Potential of Thermal Gradient Gas Chromatography (TGGC)
Thermal gradient gas chromatography (TGGC) was first developed in the 1960s to reduce the effects of peak broadening. With recent developments in technology, the technique is now being re-examined. In two new videos from LCGC TV, Milton L. Lee from Brigham Young University discusses the principles of TGGC, and the possible advantages of TGGC over traditional GC methods.
Advertisement
Advertisement
Related to this article
Gas chromatography-mass spectrometry (GC–MS) shows scarlet macaw feather scent varies by sex and mate status.
Martina Lioi pairs IP-HILIC and RP to map impurities in fatty acid–linked siRNAs
Gas chromatography-mass spectrometry (GC–MS) reveals bisphenol A and other lasting pollutants in Maricá Lagoon (Brazil) sediments.
This week, Chromatography Online covered automated GC-MS/MS testing for phthalates in oils, chemicals hidden in bioplastic packaging, troubleshooting tips for oligonucleotides and GLP-1 peptides, automated glycan profiling, NIST reference materials, and the experience of being the only woman in the laboratory.
Multidimensional chromatography cuts ion suppression in complex environmental samples by separating salts and coeluting compounds from target analytes.
The panel discusses quantitative peptide analysis, including drug substance vs. drug product complexity, recovery, and methionine oxidation risk.
Gas chromatography–quadrupole time-of-flight mass spectrometry (GC–QTOF MS) screening of dust finds 269 contaminants in homes, offices, and schools.
Advertisement
Advertisement
Trending on LCGC International
1
Conversations with Michael Dong: HPLC Columns for Pharmaceutical Analysis
2
GC–MS Reveals Sex-Linked Scents in Macaws' Feathers
3
Quantitative Analysis Challenges for GLP-1 Peptides
4
Kagan and Soai Win 2026 Nobel Prize in Chemistry for Solving the Mystery of Life's "Handedness"
5