LCGC TV: Sample Preparation
Photo Credit: UDE_Frank Preuβ
LCGC TV: Principles of In-Tube Extraction for Headspace Sampling of Beer
Torsten C. Schmidt on Novel Extraction Methods for GC Torsten C. Schmidt of the University Duisburg-Essen in Germany recently developed an in-tube extraction (ITEX) method for headspace sampling of beer prior to gas chromatography–mass spectrometry (GC–MS). In this video, he explores whether ITEX sampling can be used for all types of volatile organic compounds (VOCs) and goes on to explain what makes carbon-based nano materials good sorbents.
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Photo Credit: UDE_Frank Preuβ
LCGC TV: Torsten C. Schmidt on Novel Extraction Methods for GC
Torsten C. Schmidt from the University Duisberg-Essen in Germany discusses how solvent-free microextraction techniques in gas chromatography have developed since their introduction in the mid-1980s, and the advantages of solvent-free microextraction techniques compared to purge-and-trap enrichment.
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Photo Credit: UDE_Frank Preuβ
LCGC TV: Trends in Sample Preparation
In this new short video interview from LCGC TV, Doug Raynie of South Dakota State University discusses the niche sample preparation techniques that are becoming more popular, and comments on what is needed in the future.Watch Here >>
LCGC TV: Screening Environmental Pollutants in Water Samples
In this new video from LCGC TV, Anthony Gravell of Natural Resources Wales discusses the advantages of GCxGC for the analysis of passive sampling extracts and how GC–MS can be applied to the analysis of passive sampling extracts. Watch Here >>
LCGC TV: Trends in Sample Preparation Right Now
There are some interesting shifts going on in sample preparation. In this new short video interview, Doug Raynie of South Dakota State University discusses current trends with respect to both liquid and solid samples. Watch Here >>
LCGC TV: Frederick Lynen on the Challenges of Developing a HILIC-based SPE Approach to Analyze Biological Fluids
A single drop of blood represents a complex mixture of biological compounds including phospholipids, proteins, and salts. Frederic Lynen of Ghent University in Belgium discusses the possibilities of a HILIC-based SPE approach to remove phospholipids from blood samples, its applicability to other organic molecules, and how it benefits the chromatographer in practice. Watch here>>
LCGC TV: Rethinking Sample Prep
When we asked Doug Raynie where he sees sample preparation heading, he replied not in terms of specific techniques, but instead in terms of the overarching considerations that we should keep in mind. Do we need to rethink sample prep? Watch Here>>
LCGC TV: Sample Preparation for Chromatographic Methods in Metabolomics
Advances in mass spectrometry instrumentation have opened up the field of metabolomics, but there are still issues with non-standardized sampling and sample preparation methods. Tuulia Hyötyläinen from the VTT Technical Research Centre of Finland discusses the vast range of sample matrices and gives advice on best practices. Watch Here>>
LCGC TV: Using Passive Sampling in Environmental Analysis
Anthony Gravell of Natural Resources Wales discusses the principles of passive sampling and the advantages of the technique over spot sampling when screening water samples for environmental contaminants. He also gives an overview of the challenges and considerations that have to be made when performing LC–MS on passive sampling extracts. Watch Here>>
LCGC TV: What's Behind the Trends in Sample Preparation
There are some interesting shifts going on in sample preparation. In this new short video interview, Doug Raynie of South Dakota State University discusses what is behind the trends - starting with the fundamental differences in strategies for solid and liquid samples. Watch Here>>
Modern HPLC Strategies: Improving Retention and Peak Shape for Basic Analytes
August 16th 2024In high-performance liquid chromatography (HPLC), it is common for bases and unreacted ionized silanols on silica-based columns to cause irreproducible retention, broad peaks, and peak tailing when working with basic analytes. David S. Bell, Lead Consultant at ASKkPrime LLC offers innovative HPLC strategies that can help mitigate such issues.
Reliable Separation and Efficient Group-type Quantitation of Total Petroleum Hydrocarbons (TPHs)
September 11th 2024Petroleum contamination from leaking underground storage tanks, for example, is a significant concern for both the environment and human health. Thorough characterization of the contamination is required to form appropriate risk assessments and remediation strategies, but until now, the determination of total petroleum hydrocarbons (TPHs) in soil has typically involved a convoluted and labour-intensive process. In this article, the analysis of TPH in environmental media is simplified using flow-modulated GC×GC–FID with quantitation based on pre-defined compound groupings. This approach overcomes the drawbacks of conventional solvent fractionation approaches, by eliminating the need for sample fractionation and automating data processing workflows.
The Reality Behind Column Insertion Distance
September 10th 2024Column insertion distance is critical to good chromatography. What happens if the column is installed too low in the injection port? Is insertion distance more important when performing split injection or splitless injection? Does the position of the column in the injection port impact reproducibility?
