Multiresidue Antibiotic Analysis

Article

Scientists from the USDA';s Eastern Regional Research Center (Wyndmoor, Pennsylvania) analyzed 11 beta-lactam antibiotics in bovine kidney using a sample preparation method consisting of an acetonitrile-water extraction followed by a dispersive solid-phase extraction with a C18 sorbent, extract concentration, and filtration with syringeless filter vials.

Scientists from the USDA's Eastern Regional Research Center (Wyndmoor, Pennsylvania) analyzed 11 beta-lactam antibiotics in bovine kidney using a sample preparation method consisting of an acetonitrile-water extraction followed by a dispersive solid-phase extraction with a C18 sorbent, extract concentration, and filtration with syringeless filter vials. The final filtered extracts were analyzed by liquid chromatography-tandem mass spectrometry. The antibiotics included amoxicillin, ampicillin, cefazolin, cephalexin, cloxacillin, DCCD, deacetylcephapirin, dicloxacillin, nafcillin, oxacillin, and penicillin G.

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