New Advancements in Biopharma Protein Characterization Using HRIM
Webinar Date/Time: Friday, September 29, 2023 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
Unlock a new realm of molecular analysis in biopharma as we delve into the MOBIE® platform's unprecedented gas-phase separation capabilities, offering superior insights into isomeric N-glycans, peptide PTMs, and intact proteins. Don't miss this opportunity to discover how the MOBIE platform empowers enhanced structural understanding, increased throughput, and greater reproducibility, revolutionizing biopharmaceuticals and more.
Register Free: https://www.chromatographyonline.com/lcgc_w/biopharma-protein
Event Overview
This seminar will demonstrate the utilization of the MOBIE® platform, a high-resolution ion mobility-mass spectrometry (HRIM-MS) instrument based on structures for lossless ion manipulation (SLIM) technology. The platform provides the highest commercially available IM resolution across the full mass range for a variety of biopharma relevant applications. This technology adds a new dimension of gas-phase separation to molecular analysis and is an orthogonal technique to existing MS workflows, which enables increased throughput, additional structural insights, and higher reproducibility. This webinar will focus on peptide therapeutic relevant applications such as:
- LC-HRIM-MS characterization of released N-Glycans.
- Isomeric/isobaric post-translational modifications (PTMs).
- Intact proteins, including mAbs, using the additional dimension of gas-phase separation.
Key Learning Objectives:
- Receive an overview of SLIM technology and the MOBIE platform.
- Learn the advantages of digital separations on throughput, resolution, and reproducibility.
- Understand the real-world impact of HRIM analysis on biotherapeutic analysis.
Who Should Attend:
- Scientists, lab directors, R&D scientists, QA/QC scientists and directors
Speaker:
Greg Kilby
Distinguished Scientist
MOBILion Systems, Inc
With a distinguished career spanning more than 15 years in biopharmaceutical research, Dr Greg Kilby has emerged as a prominent figure in the realm of molecular analysis and mass spectrometry. Holding a PhD in analytical chemistry, Greg's expertise encompasses the pioneering application and development of cutting-edge ion mobility-mass spectrometry technologies. His transformative work revolves around harnessing these innovative platforms to decipher intricate biomolecular structures, shedding light on the complexities of peptide therapeutics and biopharmaceuticals. As an advocate for scientific advancement, Greg's contributions continue to shape the landscape of biopharmaceutical analysis, consistently pushing the boundaries of knowledge and discovery.
Register Free: https://www.chromatographyonline.com/lcgc_w/biopharma-protein
A Life Measured in Peaks: Honoring Alan George Marshall (1944–2025)
June 18th 2025A pioneer of FT-ICR Mass Spectrometry, Alan G. Marshall (1944–2025), is best known for co-inventing Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS), a transformative technique that enabled ultrahigh-resolution analysis of complex mixtures. Over a career spanning more than five decades at institutions like the University of British Columbia, The Ohio State University, and Florida State University, he published over 650 peer-reviewed papers and mentored more than 150 scientists. Marshall’s work profoundly impacted fields ranging from astrobiology to petroleomics and earned him numerous prestigious awards and fellowships. Revered for his intellect, mentorship, and dedication to science, he leaves behind a legacy that continues to shape modern mass spectrometry.
