|Articles|September 3, 2021
Organic Solvent in Size Exclusion Chromatography of an Antibody Drug
Author(s)Phenomenex, Inc.
In this application note, we demonstrate the effect of organic solvent on SEC analysis of an ADC “mimic.” This sample is a monoclonal antibody that has been conjugated to a dansyl group and functions as a surrogate for the typically cytotoxic agent commonly used for most ADC modalities.
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