Webinar Date/Time: Thu, May 2, 2024 11:00 AM EDT
Register to learn about overcoming AAV aggregate analysis challenges using a novel SEC chemistry. Maximize aggregate/monomer resolution, reduce sample consumption and run times, and method optimization best practices across buffer systems and serotypes.
Aggregate analysis of Adeno Associated Virus (AAV) is crucial for quality assessment and currently presents various challenges including long run times, high volume sample consumption where sample quantities are limited, and accurate quantitation of monomer and aggregate species. In this webinar, Senior Research Scientist Shilin Cheung, will review optimization of high throughput size exclusion chromatography methods using a novel 700 Å pore size SEC chemistry to reduce sample consumption and run times. Additionally, method versatility with multiple mobile phase conditions utilizing various detectors across several AAV serotypes will be explored.
Key Learning Objectives:
Who Should Attend:
Dr. Shilin Cheung
Sr. Research Scientist
Dr. Shilin Cheung received her BS (2006) and Ph.D. (2012) in Bioanalytical Chemistry from the University of Toronto. She has developed, qualified, and validated innovative analytical methods in CE based microfluidics, automated low volume UV-vis spec., and UHPLC assays. Her methods have been applied to manufacturing process developments, formulation and stability and DS/DP characterization and specification testing. At Phenomenex she is focused on developing fit for purpose analytical methods to help advance developments in gene therapeutics.
Ramkumar Dhandapani, PhD
Sr Product Manager