prominence TOX.I.S. (HPLC/PDA for identification of drugs in human urine)

August 21, 2009

Toxicological analysis of body fluids is an important task whenever acute intoxications, abuse of drugs or consumption of illicit drugs needs to be identified. Such analyses require a universal sample pretreatment and identification method and should be automated for speed and simplicity.

Toxicological analysis of body fluids is an important task whenever acute intoxications, abuse of drugs or consumption of illicit drugs needs to be identified. Such analyses require a universal sample pretreatment and identification method and should be automated for speed and simplicity.

The prominence TOX.I.S. system is based on prominence LC hardware modules using patented flow line design and column switching procedure to enable sample pretreatment of urine samples with a cleaning step, rinsing to remove proteins and other urine components, and transfer of the sample onto the analytical columns for separation.

Selection valves for the analytical columns make it possible to also use the system for analysis of blood/serum samples after a separate liquid/liquid extraction procedure or the determination of alcohol abuse marker (% CDT).

Detection and identification are achieved with photodiodearray detector and library search matches with UV spectra and relative retention time.

The application kits for the system are available from company RECIPE (www.recipe.de).

For further details visit our web page at www.shimadzu.eu