Researchers Determine the Smell of Skin Cancer Using GC-MS Techniques
Researchers from the Monell Center (Philadelphia, Pennsylvania) used GC-MS techniques to sample air above basal cell tumors and found a different profile of chemical compounds compared to the skin in healthy people. Human skin has many airborne chemical molecules known as VOCs, many of which have odors.
Researchers from the Monell Center (Philadelphia, Pennsylvania) used GC-MS techniques to sample air above basal cell tumors and found a different profile of chemical compounds compared to the skin in healthy people. Human skin has many airborne chemical molecules known as VOCs, many of which have odors. To find the changes related to cancer, the researchers first had to identify the standard profile for VOCs and determine whether it varies depending on age, gender, or body site. Their published research focuses on air sampled above two skin sites ? the forearm and the upper back- in 25 healthy men and women aged 19 to 79. The GC-MS methods helped to identify nearly 100 different chemical compounds coming from skin. The study shows odors from skin can be used to identify basal cell carcinoma, the most common form of skin cancer, and may lead to the development of new ways to find skin cancers at very early stages.
Next Generation Peak Fitting for Separations
December 11th 2024Separation scientists frequently encounter critical pairs that are difficult to separate in a complex mixture. To save time and expensive solvents, an effective alternative to conventional screening protocols or mathematical peak width reduction is called iterative curve fitting.
Identifying and Rectifying the Misuse of Retention Indices in GC
December 10th 2024LCGC International spoke to Phil Marriott and Humberto Bizzo about a recent paper they published identifying the incorrect use of retention indices in gas chromatography and how this problem can be rectified in practice.
Investigating the Influence of Packaging on the Volatile Profile of Oats
December 10th 2024In the testing of six different oat brands, headspace sorptive extraction and comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (GC×GC–TOF-MS) reveal how various packaging types can affect and alter the oats’ volatile profile, underscoring the potential impact of packaging on food quality.
The Chromatographic Society 2025 Martin and Jubilee Award Winners
December 6th 2024The Chromatographic Society (ChromSoc) has announced the winners of the Martin Medal and the Silver Jubilee Medal for 2025. Professor Bogusław Buszewski of Nicolaus Copernicus University in Torun, Poland, has been awarded the prestigious Martin Medal, and the 2025 Silver Jubilee Medal has been awarded to Elia Psillakis of the Technical University of Crete in Greece.
