SPE method to recover low concentrations of microcystins in water demonstrated

November 17, 2010

Dionex has announced a method that the company reports can fully recover low concentrations of three microcystins when added to water samples.

Dionex has announced a method that the company reports can fully recover low concentrations (

Microcystin contamination of drinking water at low nanomolar concentrations is considered a risk factor for cancer; therefore, the World Health Organization (WHO) has proposed a provisional guideline concentration of 1.0 μg/L for microcystin-LR in drinking water.

The company’s Application Note 261: Sensitive Determination of Microcystins in Drinking and Environmental Waters is reported to demonstrate recovery at lower concentrations than the maximum recommended by WHO. The company claims that this method is fully automated and easily configured on an UltiMate 3000 ×2 Dual HPLC system, using Acclaim PA2 columns for solid-phase extraction (SPE) and analysis.

This new target-cut on-line SPE method with dual function (analyte capture and partial separation) operates under automatic control of Chromeleon Chromatography Data System (CDS) software and offers full automation, absence of operator influence and strict process control.

For the application note, click here.