LCGC UST
Press Release|Articles|June 17, 2025

Streamlining (S)VOC Analysis with Automated Thermal Desorption

Thermal desorption is the gold-standard technique for analyzing volatile and semi-volatile organic compounds by GC–MS. Markes International’s technology-leading automated TD100-xr system handles up to 100 sorbent tubes in a single run, with cryogen-free operation, quantitative sample re-collection for re-analysis, and compatibility with any GC– MS. Ideal for labs seeking reliable, unattended analysis.


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Figure 2. Split injection used to measure triplicate test of MTBE, hexane, o-xylene, and 1-methylnaphthalene comparing different solvents (methanol, methylene chloride) and column insertion distances starting with 0.5 mm, 5.0 mm, 10.0 mm, 15 mm, and 20.0 mm. Methanol had the best performance at the 5.0 mm insertion distance and methylene chloride looked slightly better at the 0.5 mm. We would still recommend not going below the 5.0 mm manufacturer recommended insertion distance.
Revisiting insertion distance for methanol and methylene chloride in GC analysis and confirming that insertion depth strongly affects response and reproducibility.