
Feature|Videos|September 30, 2024
The Regulatory Stance on Oligonucleotide Enantiomers
Author(s)LCGC Editors
The panel dives into the regulatory stance on oligonucleotide enantiomers. The role of batch-to-batch reproducibility, new drug application (NDA) filing, and current guidelines are covered.
Advertisement
Episodes in this series

Regulatory guidelines must be considered when discussing oligonucleotide analysis and enantiomers. The panel reviews the current regulatory stance on this topic and common analytical bottlenecks relative to regulatory compliance.
Advertisement
Related to this article

Liquid chromatography–tandem mass spectrometry (LC–MS/MS) finds low glyphosate residues of the weedkiller glyphosate in coffee beans.

This week, Chromatography Online explored how the technique is advancing wastewater drug monitoring, siRNA method development, and food safety testing, with previews of RAFA 2026 and a return to HPLC fundamentals with Michael Dong.

Recent EU legislation on PFAS shifts from monitoring individual compounds toward managing them as a chemical class.

In this seventh part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor explains why 2.1-mm i.d. columns are less preferred for pharmaceutical quality control.

Ultrahigh-performance liquid chromatography–quadrupole time-of-flight mass spectrometry (UHPLC–QTOF-MS) shows how soaking and cooking break down soybean fats.

Liquid chromatography–tandem mass spectrometry (LC–MS/MS) links altered metabolism to lingering symptoms in Ebola survivors.
Advertisement
Advertisement
Trending on LCGC International
1
GC Reveals How Yeasts Spoil Non-alcoholic Beer
2
Conversations with Michael Dong: Why 2.1-mm i.d. Columns Are Less Preferred for Pharmaceutical Quality Control
3
AI/ML Now: Bayesian Optimization and Automation for siRNA Method Development (Part Two)
4
Mass Spectrometry Imaging in Food: The Power and the Limits
5











