TSKgel NH2-100 - a new, robust HILIC column

April 3, 2009

Hydrophilic interaction liquid chromatography (HILIC) is the preferred method for the separation of polar compounds. Tosoh Bioscience introduces a new, amino-type HILIC column with high stability.

Hydrophilic interaction liquid chromatography (HILIC) is the preferred method for the separation of polar compounds. Tosoh Bioscience introduces a new, amino-type HILIC column with high stability.

The new TSKgel NH2-100 amino columns expand the selectivity range of TSK-GEL HILIC solutions. While TSKgel Amide-80 columns are the industrial standard for the separation of Glycans by HILIC or HILIC–MS, the new column is well suited for all separations requiring amino functional groups. In contrast to conventional silica-based amino phases the new column offers expanded stability under HILIC conditions, the prerequisite for high reproducibility and reliable results. It is suited for the analysis of all types of hydrophilic compounds like carbohydrates or metabolites.

The new amino type HILIC phase is based on a 3 µm silica particle with 100 Å pores, which is treated with a special endcapping procedure. Amino groups are introduced step wisely after endcapping. The amino groups act as HILIC functional groups without any peak splits. Due to a high ligand density and large surface area TSKgel NH2-100V 3µm columns show high retention for very polar compounds. The columns are available in 2 and 4.6 mm ID and 5 or 15 cm length.

More information on www.tskgel.com

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Tosoh Bioscience
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Phone:+49 (0)711 13257-0
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[email protected]www.tosohbioscience.com