News|Articles|October 21, 2026

UHPLC-HRMS Screens Alkaloids in Cereals and Spices

A QuEChERS/ultrahigh-performance liquid chromatography and high-resolution mass spectrometry (UHPLC-HRMS) method tracks 23 plant toxins in cereals and spices. Michele Suman discusses the method with LCGC International.

Alkaloids are natural nitrogen-containing chemicals made by plants. Many people assume that natural means safe, but some alkaloids are highly toxic and have caused poisonings. They can end up in food and animal feed when toxic weeds or their seeds are accidentally harvested along with crops. As more people eat plant-based foods, food safety authorities have grown increasingly concerned about this risk.

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