PharmTech LCGC Sciex Webinar 11.10
|Articles|April 1, 2009

UHPLC-MS-MS Analysis of Alkylphenols

Researchers from Zhejiang Province Environmental Monitoring Centre (Zhejiang, China) and Xiangtan University (Hunan, China) developed an ultrahigh-pressure liquid chromatography-tandem mass spectrometry (UHPLC-MS-MS) method for analyzing alkylphenols in soil.

Researchers from Zhejiang Province Environmental Monitoring Centre (Zhejiang, China) and Xiangtan University (Hunan, China) developed an ultrahigh-pressure liquid chromatography–tandem mass spectrometry (UHPLC–MS-MS) method for analyzing alkylphenols in soil. They used pressurized liquid extraction followed by solid-phase extraction to prepare the samples for the final analysis. They used a 50 mm x 2.1 mm, 1.7-µm C18 column with gradient elution, a water–acetonitrile mobile phase, and electrospray ionization tandem MS in negative ion mode with multiple reaction monitoring to analyze the extracted alkylphenols.


Related to this article

Best of the Week: From Cancer Diagnostics to Smarter LC Method Development
This week, Chromatography Online’s coverage spanned lipidomics-based early cancer detection, career paths in separation science, machine learning and uncertainty-driven approaches to LC method development, new EU wastewater rules for pharmaceutical micropollutants, automated Separation Quality Factor (SQF) evaluation in chromatography data systems, and solutions to GLP-1 peptide analysis challenges.