UHPLC-MS-MS Analysis of Alkylphenols
Researchers from Zhejiang Province Environmental Monitoring Centre (Zhejiang, China) and Xiangtan University (Hunan, China) developed an ultrahigh-pressure liquid chromatography-tandem mass spectrometry (UHPLC-MS-MS) method for analyzing alkylphenols in soil.
Researchers from Zhejiang Province Environmental Monitoring Centre (Zhejiang, China) and Xiangtan University (Hunan, China) developed an ultrahigh-pressure liquid chromatography–tandem mass spectrometry (UHPLC–MS-MS) method for analyzing alkylphenols in soil. They used pressurized liquid extraction followed by solid-phase extraction to prepare the samples for the final analysis. They used a 50 mm x 2.1 mm, 1.7-µm C18 column with gradient elution, a water–acetonitrile mobile phase, and electrospray ionization tandem MS in negative ion mode with multiple reaction monitoring to analyze the extracted alkylphenols.
LC–MS/MS-Based System Used to Profile Ceramide Reactions to Diseases
April 26th 2024Scientists from the University of Córdoba in Córdoba, Spain recently used liquid chromatography–tandem mass spectrometry (LC–MS/MS) to comprehensively profile human ceramides to determine their reactions to diseases.
High-Throughput 4D TIMS Method Accelerates Lipidomics Analysis
April 25th 2024Ultrahigh-pressure liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) had been previously proposed for untargeted lipidomics analysis, but this updated approach was reported by the authors to reduce run time to 4 min.
