Understanding Reversed Phase Selectivity for Different Compound Classes

Understanding Reversed Phase Selectivity for Different Compound Classes

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Webinar Date/Time: Wed, Sep 27, 2023 11:00 AM EDT

Demystify reversed phase method development with this overview of column selection and mobile phase optimization. Use the tips provided to produce fit for purpose methods in a shorter time frame by using a structured approach based on analyte structure.

Register Free: https://www.chromatographyonline.com/lcgc_w/reverse-phase

Event Overview.

Are you new to HPLC method development, or maybe you would welcome a quick refresh? This webinar will show you how to select an appropriate column based on the types of molecules you are looking to separate, and then highlight how choice of mobile phase can be optimized to help maximize selectivity. The focus of this webinar will be the reversed phase separation of small molecules, considering stationary phase interactions, and the impact of mobile phase pH on retention, selectivity, and peak shape.

Key Learning Objectives:

  • Understand how to obtain good resolution by utilizing selectivity.
  • Learn the basics of different stationary phase particle characteristics.
  • Discover how to choose different stationary phases based on compound classes.
  • Find how mobile phase can be used to change the selectivity of columns.

Who Should Attend:
Any LC users who are looking for are looking for a basic overview of Reverse Phase Method Development by looking at different small molecule compound classes


Genevieve Hodson
Manager, Technical Support Team

Genevieve Hodson graduated from the University of Texas with a BS in Chemistry located in her hometown of Austin, Texas. She spent two years of her undergraduate performing research in an organic chemistry lab synthesizing intermediates. Out of school, she spent four years as an Analytical Chemist in the QC and R&D Department of Cerilliant (a Sigma Millipore Company). There, she worked with many analytical instruments but became an expert at LC by performing purity analysis, customer specific methods, validations, QC testing, and stability studies on a wide range of small molecules including pharmaceuticals, pesticides, explosives, and illegal substances. From there, she moved to Los Angeles, California where she worked at Johnson and Johnson and then a small dietary supplement company. After Genevieve spent a year living abroad in Israel raising her first son, she moved back to LA where she got hired as a Technical Specialist at Phenomenex. At Phenomenex, she enjoys continuing to learn about chromatography every day by helping customers with all their chromatography needs.

Register Free: https://www.chromatographyonline.com/lcgc_w/reverse-phase