Vol 29 No 9 LCGC North America September 2011 Application Notebook PDF

The introduction of comprehensive two-dimensional gas chromatography (GC×GC) to the sample screening toolbox has substantially increased the ability to comprehensively characterize complex mixtures. However, for many gas chromatography (GC) users, the thought of having to learn to develop methods on a new technology is daunting. Developing a basic GC×GC method for most (nonspecialized) applications can be accomplished in minimal time and effort given parameter suggestions and ranges to target analytes in a sample of interest. In this article, the authors work describe a simple workflow to develop a GC×GC method for a specific sample upon initial use, with the aim of decreasing the time to accomplish functional workflows for new users.

In high-performance liquid chromatography (HPLC), it is common for bases and unreacted ionized silanols on silica-based columns to cause irreproducible retention, broad peaks, and peak tailing when working with basic analytes. David S. Bell, Lead Consultant at ASKkPrime LLC offers innovative HPLC strategies that can help mitigate such issues.

Sartorius recently announced the release of its new Vivaflow® Tangential Flow Filtration (TFF) Cassettes, which aim to streamline tangential flow filtration (TFF) in the laboratory.

Université d’Orleans and Chromisa Scientific scientists recently created a two-dimensional supercritical fluid chromatography (SFC) system with multiple heart-cutting (MHC) modes.