Vol 33 No 6 LCGC North America June 2015 Regular Issue PDF

Kinjal Bhatt and Ina Varfaj redefine career success around energizing work and personal balance, moving past publications and promotions.

Piotr Alvarez explains how his lab uses 2D-LC to enable MS compatibility with legacy methods and to confirm peak purity through orthogonal separation.

Florian Geistmann succeeded retiring Jürgen Semmler as Shimadzu Europa managing director on October 1.

Liquid chromatography-mass spectrometry (LC-MS) profiling reveals chemical diversity across grapevine varieties.

Liquid chromatography-mass spectrometry (LC-MS) and nuclear magnetic resonance (NMR) link perinatal factors to infant urinary metabolite changes.

This LCGC Blog installment explains how NIST categorizes and certifies reference materials, and why they underpin reliable results in science and medicine.

Comparing manual and automated N-glycan profiling of a trastuzumab biosimilar, researchers found that both workflows detected the same glycan types, but automation gave more reproducible results (mean CV of about 5.7% vs. 7.95%), making it better suited to high-throughput analysis in biopharmaceutical development.

How can analysts resolve impurities that differ by a single mass unit? Experts discuss deamidation, racemization, HRMS, and 2D-LC for GLP-1 peptides.