
This article discusses the advantages of a native anion exchange method coupled to mass spectrometry (MS) for charge heterogeneity analysis of immunoglobulin G4 (IgG4)-based mAbs, which are currently being studied more intensively.
Ann Marie Rojahn studied chemistry and biotechnology in combination with an apprenticeship as a chemical laboratory assistant at the University of Applied Sciences in Krefeld, Germany. After receiving a bachelor’s degree, she pursued a master’s programme in chemistry at the University of Düsseldorf, Germany, with a focus on organic chemistry. Since 2019, she has worked for YMC Europe in Dinslaken, Germany, as a product specialist in the analytical chromatography team.

This article discusses the advantages of a native anion exchange method coupled to mass spectrometry (MS) for charge heterogeneity analysis of immunoglobulin G4 (IgG4)-based mAbs, which are currently being studied more intensively.

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The advantages of a native anion exchange method coupled to mass spectrometry for charge heterogeneity analysis of immunoglobulin G4 (IgG4)-based mAbs are described.

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