This article discusses the advantages of a native anion exchange method coupled to mass spectrometry (MS) for charge heterogeneity analysis of immunoglobulin G4 (IgG4)-based mAbs, which are currently being studied more intensively.
Daniel Eßer
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Daniel Eßer studied chemistry at the University of Applied Sciences Bonn Rhein-Sieg, in Rheinbach, Germany, with a focus on pharmaceutical and analytical chemistry. He received his Ph.D. in pharmaceutical and medicinal chemistry at the University of Düsseldorf, Germany. During his postdoc at the Institute of Pharmaceutical and Medicinal Chemistry of the University of Düsseldorf, he established a nanoLC–MS system. In 2013 he joined YMC Europe as a product specialist for analytical chromatography. Since 2017, he has been responsible for YMC’s analytical (U)HPLC column portfolio as product manager for analytical chromatography.
Articles by Daniel Eßer
This article discusses several practical examples using bioinert columns, demonstrating their ability to deliver reliable, high-resolution results with precision and reproducibility.
This article describes a comprehensive study on optimizing ion-pair reversed-phase liquid chromatography for analysing protected and unprotected single-stranded DNA oligonucleotides.
The advantages of a native anion exchange method coupled to mass spectrometry for charge heterogeneity analysis of immunoglobulin G4 (IgG4)-based mAbs are described.
What parameters can influence an siRNA separation?
This article discusses the main influences in oligonucleotide analysis using ion-pair (IP) reversed-phase chromatography.
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Latest Updated Articles
A Study on Optimum Method Conditions for Denaturated and Non-Denaturated siRNA by Ion Pair Reversed-Phase Liquid ChromatographyPublished: May 9th 2023 | Updated:
Improving Chromatographic Results for Oligonucleotides with Column HardwarePublished: February 1st 2023 | Updated:
A Study on the Optimization of the Ion-Pair Reversed Phase Liquid Chromatography Analysis of Protected And Unprotected DNA OligonucleotidesPublished: July 3rd 2024 | Updated:
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