
This article describes a comprehensive study on optimizing ion-pair reversed-phase liquid chromatography for analysing protected and unprotected single-stranded DNA oligonucleotides.
Mathias Hehn studied chemistry at TU Dortmund University, Germany, and completed his studies with PhD and postdoc research on chromatographic and spectroscopic investigations on synthetic polymers. During his subsequent industry career, he focused on liquid chromatographic stationary phases and their analytical applications for various compounds. In his current role as Head of Laboratories at YMC Europe GmbH, Dr. Hehn is responsible for providing separation solutions in both analytical and preparative applications, ranging from column packing to method development to contract work for separating synthetic compounds as well as biomolecules, including oligonucleotides.

This article describes a comprehensive study on optimizing ion-pair reversed-phase liquid chromatography for analysing protected and unprotected single-stranded DNA oligonucleotides.

Published: July 3rd 2024 | Updated: