David Sy´kora

Articles

Practical Considerations of the Influence of Organic Modifiers on the Ionization of Analytes and Buffers in Reversed-Phase LC

Daniel W. Armstrong;Eva Tesarˇová;David Sy´kora

October 1st 2002

This article provides theoretical background, experimental data, and practical considerations about the effects of organic modifiers on analyte ionization in reversed-phase LC.

Latest Updated Articles

Published: March 14th 2025 | Updated: March 28th 2025

Your Lab Deserves a Technology Upgrade

Published: November 15th 2024 | Updated: November 19th 2024

Analyzing Organic Acids in Fruit-Based Kombucha Analogues Using HPLC

Published: November 18th 2024 | Updated: November 19th 2024

LC-HRMS Technology Used to Track Chemical Migration in Reusable Plastic Bottles

Published: July 3rd 2024 | Updated: July 8th 2024

Technology Trends in Separation Science: Data Handling

Figure 1: Seven prioritization strategies in non-target screening (NTS) by chromatography–HRMS, grouped by domain: chemical information (P1–P3), toxicological information (P5–P6), external information (P4), and preprocessing (P2, P7). Each strategy narrows the candidate space based on specific criteria. Combined, they reduce complexity and focus identification on environmentally relevant features.

Published: May 19th 2025 | Updated: May 25th 2025

HPLC 2025 Preview: Prioritization Strategies in Non-Target Screening of Environmental Samples by Chromatography with High-Resolution Mass Spectrometry

Nathalie Delaunay, Audrey Combès, and Valérie Pichon © Images courtesy of authors.

Published: May 16th 2025 | Updated: May 25th 2025

HPLC 2025 Preview: Functionalized Monoliths as Selective Sample Preparation Materials

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