Diane M. Diehl | Authors

Articles

Application of Novel Ethylene Bridged Hybrid Particles for Hydrophilic-Interaction Chromatography

Using HILIC with highly efficient ethylene bridged hybrid (BEH) particles results in faster methods that exhibit improved polar retention, higher sensitivity, enhanced chromatographic resolution and significantly improved column lifetime.

A Highly Sensitive Method for the Analysis of Tamsulosin (Flomax) in Human Plasma

A highly sensitive analytical method for the analysis of tamsulosin in human plasma has been developed for use in bioanalytical studies. The solid-phase extraction (SPE) and UPLC–MS–MS methodologies are described, as well as performance against validation parameters.

A Highly Selective Method for the Analysis of Drospirenone in Human Plasma

Several common birth control formulations contain both drospirenone and ethinyl estradiol. A highly selective and sensitive analytical method for the analysis of drospirenone in human plasma has been developed for use in bioequivalence studies. The solid-phase extraction (SPE) and UPLC–MS–MS methodologies are described as well as performance against validation parameters.