Frantisek Benes | Authors

Articles

Determination of Seventeen Phytocannabinoids in Various Matrices by UHPLC–HRMS/MS

A simple ultrahigh-performance liquid chromatography high resolution tandem mass spectrometry (UHPLC−HRMS/MS) method to determine seventeen phytocannabinoids was developed and validated for Cannabis plants, resins and their extracts, and oils. The analysis was challenging because of the complexity of matrices, the large differences in the concentration of phytocannabinoids and their pattern in various cultivars, and the structural similarity of these analytes.