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Heather Longden

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Can We Continue to Draw the Line?

Heather Longden;R.D. McDowall
December 1st 2019

Chromatographic peak integration continues to be a major regulatory issue and was first discussed in this column in 2015. Is the approach to manual intervention and manual integration outlined still acceptable in the light of regulatory citations and guidance documents published since then?

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Data Handling

Andrew Anderson;John Sadler;Heather Longden
March 1st 2018

A snapshot of key trends and developments in the data handling sector according to selected panelists from companies exhibiting at Analytica 2018.

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Figure 1: Seven prioritization strategies in non-target screening (NTS) by chromatography–HRMS, grouped by domain: chemical information (P1–P3), toxicological information (P5–P6), external information (P4), and preprocessing (P2, P7). Each strategy narrows the candidate space based on specific criteria. Combined, they reduce complexity and focus identification on environmentally relevant features.
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