I.S. Krull

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Ion Mobility Spectrometry (IMS): How It Works and Its Use in Biotechnology

Ion Mobility Spectrometry (IMS): How It Works and Its Use in Biotechnology

I.S. Krull;A.S. Rathore;Jared Auclair
November 1st 2020

IMS is a valuable tool for biopharmaceutical analysis. Two formats in particular have proven useful: cyclic IMS and structures for lossless manipulations (SLIM).

Utility of Hydrogen-Deuterium Exchange Together with Mass Spectrometry for Determining Higher Order Structures of Proteins: Comparisons Between Biosimilar and Innovator Biopharmaceuticals

Utility of Hydrogen-Deuterium Exchange Together with Mass Spectrometry for Determining Higher Order Structures of Proteins: Comparisons Between Biosimilar and Innovator Biopharmaceuticals

I.S. Krull;A.S. Rathore;Jared Auclair
November 1st 2019

Hydrogen–deuterium exchange–mass spectrometry enables determination of higher order structures of biopharmaceuticals and direct comparisons between a biosimilar and its proprietary analog.

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