A.S. Rathore

Articles

Ion Mobility Spectrometry (IMS): How It Works and Its Use in Biotechnology

November 1st 2020

IMS is a valuable tool for biopharmaceutical analysis. Two formats in particular have proven useful: cyclic IMS and structures for lossless manipulations (SLIM).

Utility of Hydrogen-Deuterium Exchange Together with Mass Spectrometry for Determining Higher Order Structures of Proteins: Comparisons Between Biosimilar and Innovator Biopharmaceuticals

I.S. Krull;A.S. Rathore;Jared Auclair

November 1st 2019

Hydrogen–deuterium exchange–mass spectrometry enables determination of higher order structures of biopharmaceuticals and direct comparisons between a biosimilar and its proprietary analog.

Requirements for Validating a Capillary Isoelectric Focusing Method for Impurity Quantitation

A.S. Rathore;R.R. Kurumbail;A.M. Lasdun

November 1st 2002

The guest authors present a strategy for validating a capillary isoelectric focusing method intended to quantitate impurities in a protein drug substance.