PharmTech LCGC Sciex Webinar 11.10

Lindsey Shear

Articles by Lindsey Shear

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The Column

Recent advances in vacuum ultraviolet (VUV) spectroscopy have allowed for the application of this technology as a chemical detection platform for gas chromatography (GC). This technique is known as GC–VUV. A GC–VUV detector can produce highly characteristic absorbance spectra for nearly all chemical species in the wavelength region of 125–240 nm. This enables not only identification but also robust quantitation of a variety of compounds separable by gas chromatography, including water. This article describes the results of a pilot study focused on trace water determination in common organic solvents using an ionic liquid stationary phase GC column in a GC–VUV platform.