In an era where “more data in less time” is expected, bioanalytical scientists have had to become more resourceful. Consequently, bioanalytical laboratories are adopting and extending the use of high-resolution mass spectrometry (HRMS) and, in particular, time-of-flight high-resolution mass spectrometry (TOF-HRMS). One of the key benefits of TOF-HRMS is consistent resolution, sensitivity, and mass accuracy - even at high scan speeds with large molecules being analyzed.