- About
- Advertise
- Author Guidelines
- Contact MJH
- Editorial Advisory Board
- Ethics Policy
- Do Not Sell My Personal Information
- LCGC Staff
- Privacy Policy
- Permissions
- Subscriptions
- Terms and Conditions
© 2023 MJH Life Sciences™ and Chromatography Online. All rights reserved.
Paul Wrezel | Authors
Articles
Assay for ppm Levels of Azide in Drug Substances
The removal of azide as a potential impurity from a drug substance may be critical to its safety profile. The quantitation of this impurity is an important control parameter. This article describes a simple and practical assay for azide using chemical derivatization and HPLC. The method is shown to be suitable for the intended purpose on three example test materials. Potential issues for wider applications are discussed.
Assay for Parts-Per-Million Levels of Azide in Drug Substances
The removal of azide as a potential impurity from a drug substance may be critical to its safety profile. The quantitation of thi impurity is an important control parameter. This article describes a simple and practical assay for azide using chemical derivatization and HPLC.
Assay for Parts-Per-Million Levels of Azide in Drug Substances
A simple and practical assay for azide using chemical derivatization and high performance liquid chromatography.
Effect of Varying Co-Solvents in SFC Method Development on a Whelk-O 1® Chiral Stationary Phase
Supercritical Fluid Chromatography (SFC) is quickly becoming a popular choice by chromatographers for analytical and preparative separations.
Effect of Varying Co-Solvents in SFC Method Development on a Whelk-O 1® Chiral Stationary Phase
Supercritical Fluid Chromatography (SFC) is quickly becoming a popular choice by chromatographers for analytical and preparative separations.