All PublicationsLCGC InternationalLCGC North AmericaLCGC EuropeLCGC Asia PacificLCGC SupplementsThe ColumnE-BooksThe Application Notebook
Columns
All NewsInterviews
All App NotesBiological, Medical, and ClinicalBiopharmaceuticalsCannabisChiralEnvironmentalFood and BeverageGCGC-MSGeneralIndustrialLCLC-MSMedical/BiologicalMisc TechniquesPharmaceuticalsPolymersSample PrepSize-Exclusion Chromatography (SEC)Supercritical Fluid Chromatography (SFC)
Conference CoverageConference Listing
All WebcastsChromAcademy
ProductsE-BooksChromTubeEventsAnalytically Speaking PodcastPodcastsPodcast SeriesSponsored VideosQ&AsSponsored ContentContent Engagement HubsTips & TricksIndustry InsightsCareer OpportunitiesPeer Exchange
DirectorySubscribe
Analytical Instrumentation
Analytical Theory
Biological, Medical, and Clinical Analysis
Biopharmaceutical Perspectives
Biopharmaceuticals and Protein Analysis
Cannabis Analysis
Capillary Electrophoresis
Chiral Chromatography
ChromAcademy
Corporate Profiles
Data Acquisition, Handling, and Archiving
Data Analysis, Statistics, and Chemometrics
Dietary Supplements Analysis
Environmental Analysis
Field-Flow Fractionation (FFF)
Food and Beverage Analysis
Forensics, Narcotics
From the Editor
GC–MS
Gas Chromatography (GC)
HILIC
HPLC
Ion Chromatography
LCGC Interviews
LCGC TV: Gas Chromatography
LCGC TV: Hyphenated Techniques
LCGC TV: Liquid Chromatography
LCGC TV: Sample Preparation
LC–MS
Liquid Chromatography (LC/HPLC)
Market Profiles
Mass Spectrometry
Medical/Biological
Multidimensional GC
Multidimensional LC
Peer-Reviewed Articles
Pharmaceutical Analysis
Preparative-Scale Chromatography
Process Analytical Technology (PAT)
Quality Control/Quality Assurance (QA/QC)
Quality by Design (QbD)
Regulatory Standards, GLP and GMP Compliance
Sample Preparation
Size-Exclusion Chromatography (SEC)
Solid-Phase Extraction (SPE)
Supercritical Fluid Chromatography (SFC)
Supercritical Fluid Extraction (SFC)
The Next Generation
Thin Layer Chromatography
Trends
UHPLC
Web of Science
Spotlight -
  • Agilent Technologies Battery Summit
  • Advances in Gas Chromatography
  • The 2025 LCGC International PFAS Summit
IS1

  • Applied Clinical Trials

  • BioPharm International

  • Cannabis Science and Technology

  • Chromatography Online

  • Nutritional Outlook

  • Pharmaceutical Commerce

  • Pharmaceutical Executive

  • Pharm Tech

  • Spectroscopy Online

  • Turbo Machinery Magazine

Analytical Instrumentation
Analytical Theory
Biological, Medical, and Clinical Analysis
Biopharmaceutical Perspectives
Biopharmaceuticals and Protein Analysis
Cannabis Analysis
Capillary Electrophoresis
Chiral Chromatography
ChromAcademy
Corporate Profiles
Data Acquisition, Handling, and Archiving
Data Analysis, Statistics, and Chemometrics
Dietary Supplements Analysis
Environmental Analysis
Field-Flow Fractionation (FFF)
Food and Beverage Analysis
Forensics, Narcotics
From the Editor
GC–MS
Gas Chromatography (GC)
HILIC
HPLC
Ion Chromatography
LCGC Interviews
LCGC TV: Gas Chromatography
LCGC TV: Hyphenated Techniques
LCGC TV: Liquid Chromatography
LCGC TV: Sample Preparation
LC–MS
Liquid Chromatography (LC/HPLC)
Market Profiles
Mass Spectrometry
Medical/Biological
Multidimensional GC
Multidimensional LC
Peer-Reviewed Articles
Pharmaceutical Analysis
Preparative-Scale Chromatography
Process Analytical Technology (PAT)
Quality Control/Quality Assurance (QA/QC)
Quality by Design (QbD)
Regulatory Standards, GLP and GMP Compliance
Sample Preparation
Size-Exclusion Chromatography (SEC)
Solid-Phase Extraction (SPE)
Supercritical Fluid Chromatography (SFC)
Supercritical Fluid Extraction (SFC)
The Next Generation
Thin Layer Chromatography
Trends
UHPLC
Web of Science
IS1

  • Applied Clinical Trials

  • BioPharm International

  • Cannabis Science and Technology

  • Chromatography Online

  • Nutritional Outlook

  • Pharmaceutical Commerce

  • Pharmaceutical Executive

  • Pharm Tech

  • Spectroscopy Online

  • Turbo Machinery Magazine

    • Columns
    • Directory
    • Subscribe
Advertisement

Shinji Nagai

home / authors / shinji-nagai

Shinji Nagai is with Hitachi High-Technologies, Hitachinaka, Ibaraki, Japan.

Articles

Identification of a Low-Abundant Biomarker in Human Serum Using nanoLC–LIT-TOF MS and Information-Based Acquisition Techniques

Identification of a Low-Abundant Biomarker in Human Serum Using nanoLC–LIT-TOF MS and Information-Based Acquisition Techniques

Susumu Watanabe;Shinji Nagai;Chad Ostrander;Yukie Sasakura;Jennifer Krone;Katsuhiro Kanda;Makato Nogami
November 1st 2006

Serum protein profiling using mass spectrometry (MS) is one of the most promising approaches for biomarker identification.

Latest Updated Articles

Your Lab Deserves a Technology Upgrade
Published: March 14th 2025 | Updated: March 28th 2025
Your Lab Deserves a Technology Upgrade
Analyzing Organic Acids in Fruit-Based Kombucha Analogues Using HPLC
Published: November 15th 2024 | Updated: November 19th 2024
Analyzing Organic Acids in Fruit-Based Kombucha Analogues Using HPLC
LC-HRMS Technology Used to Track Chemical Migration in Reusable Plastic Bottles
Published: November 18th 2024 | Updated: November 19th 2024
LC-HRMS Technology Used to Track Chemical Migration in Reusable Plastic Bottles
Technology Trends in Separation Science: Data Handling
Published: July 3rd 2024 | Updated: July 8th 2024
Technology Trends in Separation Science: Data Handling
Chat bot intelligence Ai. Businessman using chat in smartphone Chat with AI Artificial Intelligence, developed by OpenAI generate. Futuristic technology, robot in online system. | Image Credit: © Kiattisak - stock.adobe.com
Published: May 13th 2025 | Updated: May 17th 2025
Biopharmaceutical Characterization in the Age of Artificial Intelligence
Pipette, liquid and test tube in laboratory for science experiment, chemical analysis and sample preparation. Equipment, closeup and dropper for medical research, biochemistry and solution mixing. | Image Credit: © CoetzeeRising/peopleimages.com
Published: May 13th 2025 | Updated: May 17th 2025
Sample Preparation of Drug Substances and Products in Regulated Testing: A Primer
About
Advertise
Author Guidelines
Contact Us
Editorial Advisory Board
Ethics Policy
Do Not Sell My Personal Information
Privacy Policy
Permissions
Subscriptions
Terms and Conditions
Contact Info

2 Commerce Drive
Cranbury, NJ 08512

609-716-7777

© 2025 MJH Life Sciences

All rights reserved.
Home
About Us
News