Shiseido Co., Ltd. | Authors


Increased Resolution and Reproducibility with TSKgel® UP-SW3000 Columns Versus a Competitive Column

TSKgel UP-SW3000 columns are 2 µm SEC columns designed for the analysis of monoclonal antibodies and other biopharma products. Higher resolution can be achieved for the separation of antibody monomers, dimers, and higher order aggregates with a TSKgel UP-SW3000 column compared to a competitor UHPLC column. The TSKgel UP-SW3000 column provided excellent reproducibility for the peak parameters of retention time, asymmetry, and column efficiency. As demonstrated by the %RSD values, injection-to-injection reproducibility was superior to the competitor column.

Characteristics and Application of a Chiral Column, Chiral CD-Ph

In recent years, in the course of pharmaceuticals purified, as the need to chiral purification decreased since the improving of the asymmetric synthetic techniques, the desire to make medicine effective yet with a smaller number of doses and promised safety has raised