Automated Workflow Paves Way for High-Throughput Reproducible Operations—Trastuzumab Glycosylation Profiling as a Case Study
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Comparing manual and automated N-glycan profiling of a trastuzumab biosimilar, researchers found that both workflows detected the same glycan types, but automation gave more reproducible results (mean CV of about 5.7% vs. 7.95%), making it better suited to high-throughput analysis in biopharmaceutical development.