Stephen Smith | Authors


Characterization of Allergens in Cosmetics by GC×GC–TOF-MS with Variable-Energy Electron Ionization

The detection and quantitation of allergens in complex cosmetics extracts using two-dimensional gas chromatography–time-of-flight mass spectrometry (GC×GC–TOF-MS) is described. In particular, variable-energy electron ionization is shown to enhance both the sensitivity and selectivity of analyses by generating mass spectra containing structurally significant fragment ions with an improved molecular ion signal.