A multilaboratory collaborative study organized by the Human Proteome Organization demonstrated that participating laboratories had difficulty in identifying components of a simple protein mixture.
Following the sequencing of the human genome, the biological science community has moved to tackle the human proteome.
ERLIC is a new technique that shows promise as an alternative or complementary technique for both enrichment and separation of these posttranslationally-modified peptides.
A number of commercial in-solution, and in-gel IEF fractionation systems are described in this month's column.
This installment of "Directions in Discovery" will review current phosphorylation enrichment techniques with a focus on new developments.
In the last year, two new protein depletion products have been introduced, and these will be the focus of this month's installment of "Directions in Discovery."