WR Grace

Free enzymes suffer from inconsistent performance and are difficult to recover and reuse. Immobilizing enzymes on silica resin offers a practical and efficient solution for biocatalysis reactions, enabling reproducibility, consistency, and cost-effectiveness at scale. Grace’s DAVISIL® silica resins offer a smart solution for immobilizing enzymes and are available in a wide range of pore sizes, particle sizes and chromatography phases. Discover how solid silica supports from Grace can transform your process.

Particularly in the pharmaceutical industry, drug purity isn’t just a goal – it’s essential for achieving safety, stability and efficacy. However, purification is easier said than done, especially with challenging molecules like DNA and RNA “oligonucleotides,” due in large part to their diversity and the range of impurities that can be generated during production. Enter DAVISIL® chromatographic silica, with a wide range of pore diameters and particle sizes to meet your specific application, performance and sustainability requirements. Before you choose the chromatography resin for your next purification application, take a look at these 5 considerations.

Separation of free fatty acids from triglycerides can be inefficient and challenging, resulting in low yields. Whether using supercritical fluid chromatography or standard liquid chromatography, discover why DAVISIL® Chromatographic Silica has been referenced in third-party publications as the preferred separation medium because of its greater capacity. Learn more about Omega-3 Fatty Acids purification from Fish Oil in this technical data sheet.

Not all chromatography resins are created equal. Off-the-shelf chromatography resins might not always meet the rigorous purification requirements of biopharmaceutical manufacturing. Custom bonded silica from Grace can address a wide range of separation challenges, leading to real performance improvements. Discover more about the latest innovations in chromatography silica from Grace, including VYDAC® and DAVISIL®.