The Column-01-20-2020

Aogu Furusho from the Graduate School of Pharmaceutical Sciences in Kyushu University, Fukuoka, Japan, spoke to us about his development of a highly selective three-dimensional chiral high performance liquid chromatography (HPLC) system for the determination of extraterrestrial amino acids in carbonaceous chondrites.

The chemistry of samples analyzed using gel permeation chromatography/size-exclusion chromatography/gel filtration chromatography (GPC/SEC/GFC) is very diverse. Different chemistries of stationary phases are required to allow for true size separation. Several types of materials are available, all of which have their advantages and limitations. While silica‑based stationary phases are most common in high performance liquid chromatography (HPLC), for macromolecules polymer-based phases are popular.

SepSolve Analytical Ltd has successfully relocated its headquarters to a new and larger premise in Peterborough, UK.

Researchers have developed a headspace gas chromatography-ion mobility spectrometry (HSGC–IMS) method to detect volatile organic compounds (VOCs) linked to Alzheimer’s disease in faeces and urine.

Food safety scientists have validated a new method to detect neurotoxins in seafood products using UHPLC–HILIC–MS/MS.

PCDDs, PCDFs, and PCBs are toxic compounds categorized as POPs and are ubiquitous throughout the world. Detecting trace levels of PCDD and PCDF is important to monitor food supplies and to ensure industrial emissions meet regulatory standards. In line with the ongoing innovation in dioxin analysis technology, the US EPA is currently evaluating a new method-APGC–MS/MS-for PCDD and PCDF confirmatory analysis. Joe Romano and Douglas Stevens from Waters Corporation discuss the benefits of this new method.

The improved performance of chromatographic detectors, most notably mass spectrometers (MS), has enabled many advances in analytical science, however, one such advance may be given less prominence than perhaps it should.

Click the title above to open The Column January 2020 Europe & Asia issue, Volume 16, Number 1, in an interactive PDF format.

Click the title above to open The Column January 2020 North American issue, Volume 16, Number 1, in an interactive PDF format.