The Column-05-06-2016

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The Column

Researchers from Colorado State University have demonstrated the viability of exploratory metabolomics and HILIC–MS in identifying biomarkers associated with dengue virus (DENV) infections, such as dengue fever, dengue haemorrhagic fever/dengue shock syndrome (DHF/DSS).

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The Column

Nanoparticles hold enormous potential for targeted, well-controlled drug delivery. Extensive characterization of nanoscale drug-delivery vehicles is essential to ensure their efficacy and reproducibility. While various methods are available to characterize nanoparticle size, including dynamic light scattering (DLS), electron microscopy, and nanoparticle tracking analysis, field-flow fractionation–multi-angle light scattering (FFF–MALS) is one of the most versatile techniques to determine size, structure, and other properties. This article highlights a study demonstrating the benefits of FFF–MALS–DLS for the characterization of nanolipid particles.