The Column-07-22-2016

Waters Corporation has announced a collaboration with the Bioprocessing Technology Institute (BTI), a research institute within Singapore’s Agency for Science, Technology, and Research.

Researchers from Vienna University of Technology (TU Wien), Austria, have used chip capillary electrophoresis (CE) in combination with molecular beacons (MBs) to analyze the release of the RNA genome from a human rhinovirus.

The University of Manchester unveiled the £18-million Stoller Biomarker Discovery Centre at the beginning of June 2016. The research centre will focus on biomedical research on major diseases, including cancer, psoriasis, and arthritis, using mass spectrometry (MS)‑based proteomics solutions from Sciex.

Kevin A. Schug considers what the study of chemometrics and experimental design statistics can add to an analytical chemist’s work. Do analytical chemists lack an appreciation for the mathematical and statistical tools used to tease out important information?

Preview of the International Symposium on GPC/SEC and Related Techniques.

The Column
Features

July 22, 2016

Raquel Garcia and Maria João Cabrita reveal the theory and practical applications of molecularly imprinted polymers (MIPs).

Click the title above to open The Column July 22, 2016 Europe & Asia issue, Volume 12, Number 13, in an interactive PDF format.

Click the title above to open The Column July 22, 2016 North American issue, Volume 12, Number 13, in an interactive PDF format.

The Column

In clinical and forensic/toxicology laboratories, urine is a preferred matrix from which to quantify drug concentrations because it yields accurate results and allows for noninvasive collection methods. Prior to excretion, drug metabolites in the body undergo a glucuronidation reaction, resulting in a glucuronide bond that must be cleaved before mass spectrometry (MS) analysis by a β-glucuronidase enzyme hydrolysis. Many laboratories employ a “dilute-and-shoot” method after hydrolysis to decrease residual protein or enzyme concentration, but this method negatively affects column lifetime and reduces the sensitivity of analyte detection. By using a β-glucuronidase removal approach, analysts are able to see an increase in sensitivity and a reduction in MS instrument maintenance.

The Column
Cover Story

July 01, 2016

Incognito debates the pros and cons of onshore support.