LCGC Asia Pacific-06-01-2017

LCGC Asia Pacific

Method Adjustment the USP Way

June 12, 2017

LC Troubleshooting

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When you want to adjust a United States Pharmacopeia (USP) method for a different size column or to meet system suitability criteria that fail, how much of a change can you make without revalidating the method?

Extraction of Micropollutants From Size-Limited Solid Samples

June 12, 2017

Cover Story

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The quantitative extraction and subsequent purification of trace contaminants from (semi-)solid environmental and food matrices of regular size (that is, a few grams) is still recognized as a challenging task, typically accomplished through relatively complex off-line multistep treatment procedures. When these conventional sample preparation procedures are applied to the treatment of size-limited samples (of less than 1 g), the difficulties increase. This review discusses the different analytical strategies that can be adopted to overcome (or at least reduce) these difficulties when chromatographic techniques are involved for final instrumental determination.

Vol 20 No 2 LCGC Asia Pacific June 2017 Regular Issue PDF

June 01, 2017

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Click the title above to open the LCGC Asia Pacific June 2017 regular issue, Vol 20, No 2, in an interactive PDF format.