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In this issue of “Hot Topics in Mass Spectrometry,” we highlight the role of ion mobility mass spectrometry (IM-MS) in addressing challenges in omics research, such as resolving isomeric ambiguity and enhancing sensitivity for low-abundance analytes, how selected ion flow tube mass spectrometry (SIFT-MS) is being used to conduct objective odor analysis in food and environmental samples, and the importance of sample preparation in quantitative bioanalysis.
