 a chart covering possible causes and solutions for lack of sensitivity.

Articles

Articles in this Issue

Sensitivity

 a chart covering possible causes and solutions for decreasing (or lower-than-expected) pressure, fluctuating pressure, high back pressure, and increasing pressure.

Pressure

 a chart covering possible causes and solutions for no peaks, broad peaks, ghost peaks, negative peaks, peak doubling or splitting, peak fronting, peak tailing, and peak spikes.

Peaks

 a chart covering possible causes and solutions for changing retention times, decreasing retention times, increasing retention times, and retention beyond total permeation volume (size exclusion chromatography).

Retention

 to view a chart covering possible causes and solutions for disturbance at void time, drifting baseline, and noise.

Baseline

 to view a chart covering possible causes and solutions for leaks at columns or fittings, detectors, injection valves, pumps, and UHPLC.

Leaks

 a chart covering possible causes and solutions for poor sample recovery.