LCGC Europe-06-01-2016

Different techniques of liquid chromatography (LC) mobile-phase mixing can give different results and have different problems.

In the world of data integrity, the focus is typically on the data and the numbers. How can technology, such as a laboratory information management system (LIMS), help to ensure data integrity?

This yearly report on new products introduced at Pittcon or in the preceding year covers instruments, accessories, and sorbents for sample preparation.

The third instalment in this series provides an overview of modern practices of separation science in small-molecule drug development. It highlights approaches in high performance liquid chromatography (HPLC) method development and physical or chemical characterization to support process chemistry and formulation development, and for assessment or control of clinical trial materials. The roles of separation scientists in analytical development and salient chromatographic methodology trends are also discussed.

The 18th International Symposium on Advances in Extraction Technologies (ExTech’2016) and the 22nd International Symposium on Separation Sciences (ISSS’2016) will be held at the Cultural and Congress Centre “Jordanki”, Torunˊ, Poland, from 3–6 July 2016.

An excerpt from LCGC’s e-learning tutorial on GC analysis at CHROMacademy.com

Click the title above to open the LCGC Europe June 2016 regular issue, Vol 29, No 6, in an interactive PDF format.

Chromatography connected with ion mobility spectrometry (IMS) is not commonly used, but is being investigated more. IMS is an independent analytical technique with very good detectability and a rather small separation ability. One favourable property of IMS is that it can work with ambient pressure and can be easily connected to a gas chromatograph. Analytical applications of GC–MS are very different and encompass investigations into food, medical science, environment, drugs of abuse, chemical warfare agents, and explosives.