LCGC Europe-09-01-2007

Event News
LCGC Europe

September 01, 2007

FACSS, the Federation of Analytical Chemistry and Spectroscopy Societies, will hold this year's annual conference from 14–18 October, at the Memphis Cook Convention Center, Memphis, Tennessee, USA. It will cover analytical chemistry with an emphasis on spectroscopy. Bringing together leading scientists across many disciplines for scientific exchange, the exhibition also provides a variety of informal networking opportunities.

LCGC Europe
Gas Chromatography

September 01, 2007

In addition to the universal detectors used in gas chromatography (GC), selective detectors have also played an important role in the rapid spreading of the utilization of the technique. Probably the most important selective GC detector is the electron-capture detector, with a very high sensitivity to organic compounds containing chlorine and fluorine atoms in their molecules. The electron-capture detector had a vital role in environmental protection and control - its use helped to prove the ubiquitous presence of chlorinated pesticides in nature and halocarbons in our atmosphere, and made us aware of the global extent of pollution. It was the electron-capture detector that made concentration ranges of parts-per-billion (ppb: 1:109) or even parts-per-trillion (ppt: 1:1012) detectable. Today, these terms are used routinely without realising how formidable such a sensitivity really is: 1 ppb means that a spaceship (or a UFO, depending upon one's inclination) could pick up a particular family of six from..

LCGC Europe
New Technologies

September 01, 2007

Easy-to-use multimemory card reader; Presentations with a new wireless twist; Multimedia wristwatch has arrived; Space cube is a computer with a tiny difference

Size-exclusion chromatography (SEC) and pyrolysis-gas chromatography (Py-GC) are commonly used to characterize copolymers. SEC is a powerful method to determine the molecular-weight distribution of polymers whereas Py-GC provides valuable information on their chemical composition. The combination of these two techniques could yield combined size and composition information for copolymers or polymer mixtures. A fully automated system was constructed to perform these two-dimensional (2D) characterizations. Several examples of the use of this new technique to comprehensively characterize polymers are described.

The evaluation of the state of a biological sample before starting the complex analyses is a crucial step in proteomics studies. This paper compares planar polyacrylamide gel electrophoresis (SDS-PAGE) and capillary on-the-chip SDS GE (CGE-on-the-chip) in terms of the speed of analysis, sensitivity and flexibility. Snake venoms, which are heterogeneous with high bioactivity and consist mainly of proteins with a molecular weight mass range below 100 kDa, were investigated. CGE-on-the-chip was found to be a faster and more stable technique, providing more information than classical SDS-PAGE. CGE-on-the-chip was also capable of detecting many compounds over a broad molecular weight mass range whereas the SDS-PAGE is more time-consuming and provides acceptable resolution either in the very low (below 17 kDa) or in the mid- to high-molecular mass region (16–200 kDa) depending on the gel/buffer-system selected.

LCGC Europe
LC Troubleshooting

September 01, 2007

Different methods require different strategies.