Quantitative Metrics to Properly Describe Solute Elution in Size-Exclusion Chromatography
February 16th 2024The purpose of this short tutorial article is to review the terms and official nomenclatures for size-exclusion separations and to provide some guidance and recommendations for practicing chromatographers. The interconversion between the different metrics is explained and some examples are presented.
The 2024 Lifetime Achievement and Emerging Leader in Chromatography Awards
February 1st 2024Wolfgang F. Lindner and Martina Catani are the winners of the 17th annual LCGC Lifetime Achievement and Emerging Leader in Chromatography Awards, respectively. These awards honor the work of talented separation scientists at different stages in their career. The award winners will be honored in March in an oral symposium at the Pittcon 2024 conference in San Diego, California.
Ingenious Ways to Manipulate Peak Integration?
February 1st 2024Tired of life as your analytical results are always out of specification (OOS)? Fed up with yet another laboratory investigation? Get those rotten chromatograms to generate passing results by learning ways to manipulate peak integration from the experts... and now I have your undivided attention...and how reviewers, QA and inspectors can detect them!
Separation of All Classes of Carbohydrates by HPAEC-PAD
High performance anion-exchange chromatography coupled with pulsed amperometric detection (HPAEC-PAD) is a potential method of choice for the analysis of carbohydrates.
The Gradient Delay Volume, Part II: Practice – Effects on Method Transfer
February 1st 2024In this installment, I illustrate the impact of different gradient delay volumes when transferring a method between instruments and discuss some strategies that can be used to mitigate these challenges.
Quantitative Determination of Four Lignans in Phyllanthus niruri L. by HPLC
February 1st 2024A simple analytical method using high performance liquid chromatography (HPLC) with ultraviolet (UV) detection was developed for the simultaneous determination of four main lignans (niranthin, nirtetralin B, hypophyllanthin, and phyltetralin) in Phyllanthus niruri L. plant samples from Guangxi province.