LCGC North America-05-01-2001

This installment of "Sample Prep Perspectives" discusses microdialysis sampling and the opportunities and challenges it presents. The guest authors look at microdialysis theory and equipment and describe potential applications...

Autosamplers can be great time-savers, but they have their own set of problems...

On the occasion of the 60-year anniversary of the invention of partition chromatography and the 50-year anniversary of the introduction of gas-liquid partition chromatography, this installment of Milestones in Chromatography discusses the circumstances that led to these developments...

In this article, the authors review recent developments in the research of whole-column-imaging detection for capillary electrophoresis (CE). Whole-column-imaging detection was developed for capillary isoelectric focusing, for which it proved to be an ideal detector. Several whole-column-imaging detectors -- including refractive index gradient imaging, UV-absorption imaging, and fluorescence imaging detectors -- have been studied. The capillary isoelectric focusing UV-absorption imaging technique even has been commercialized. The development of whole-column-imaging detection itself facilitates CE studies in many directions such as in electrophoretic dynamics within narrow channels, new separation modes, and two-dimensional separations. Whole-column-imaging detection also finds application in capillary zone electrophoresis.

The authors investigated the analytical capabilities of quadrupole, time-of-flight, and Fourier transform mass analyzers for liquid chromatography electrospray mass spectrometry (LC-MS) applications.

This month in GC Connections, John Hinshaw presents his report of new gas chromatography instruments and accessories exhibited at the 52nd Pittsburgh Conference...