LCGC North America-07-01-2013

The underlying principles of gradient elution HPLC are very different from those of the isocratic mode. Appreciating the differences can lead to better methods.

Long-distance running is examined as a metaphor for gas chromatography separations.

Evidence to demystify HPLC and UHPLC column myths

A method is described that incorporates a mobile-phase gradient consistent with a HILIC separation mechanism and uses a mixed-mode column, which provides reversed-phase and cation-and anion-exchange properties, and charged aerosol detection.

Can anything be done to correct for baseline drift in gradient separations?

Davy Guillarme discussed the possibilities and limitations of HILIC in a recent web seminar. Here, he answers common questions about the method.

Peter Carr and Davy Guillarme, the 2013 winners of the LCGC Lifetime Achievement and Emerging Leader in Chromatography Awards, respectively, will be honored this fall at the SciX 2013 conference.

This column installment traces the early development of SEC from its inception to its acceptance as a modern analytical technique.

Gas chromatography–mass spectrometry (GC–MS) combines a gas chromatographic front-end separation with a mass spectrometer.

Click the title above to open the LCGC North America July 2013 regular issue, Vol 31 No 7, in an interactive PDF format.