Current Trends in Mass Spectrometry | LCGC Supplements

A Novel Mass Spectrometry Paradigm to Analyze Classical and New Biotherapeutic Modalities

May 01, 2023

Featured Articles

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A new fragmentation approach—tunable electron-activated dissociation (EAD) tandem mass spectrometry (MS/MS)—offers a solution to better improve the detection and characterization of impurities in lipid nanoparticles and impurities in other biopharmaceutical modalities.

An LC–MS/MS Method for the Evaluation of Intestinal Permeability in Blood Plasma

May 01, 2023

Featured Articles

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A rapid and robust LC–MS/MS method for determining lactulose and rhamnose concentrations in blood plasma was used to determine intestinal permeability from blood plasma, which can help diagnose gastrointestinal diseases such as Crohn’s disease.

Analysis of PFAS in Locally Acquired Food Containers

May 01, 2023

Peer-Reviewed Article

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The combination of an untargeted approach using ultrahigh pressure liquid chromatography–quadrupole time-of-flight mass spectrometry (UHPLC–QTOF) and a targeted approach using UHPLC–tandem mass spectrometry (MS/MS) are presented as an ideal method for detecting per- and polyfluroalkyl substances (PFAS) in fast-food packaging.