Mark Perkins is a senior applications chemist and SIFT-MS expert at Element Materials Technology (formerly Anatune), based in Cambridge, United Kingdom. Mark graduated from the University of Southampton, UK, with a Ph.D. in electrochemistry. He was with the Malaysian Rubber Board’s UK research centre for 12 years, first as a senior analyst, then as head of the analytical section. He joined Element in early 2015 in a role that supports and expands the analytical capability of SIFT-MS—with a particular focus on autosampler integration and the development of automated test methods. Direct correspondence: mark.perkins@element.com
Rapid Quantitative Analysis of Ethylene Oxide and 1,4-Dioxane in Polymeric Excipients Using SIFT-MS
Pharmaceutical excipients, such as polyethylene glycol-based polymers, must be tested for the presence of ethylene oxide (EtO) and 1,4-dioxane as part of a safety assessment, according to USP Chapter <228>.
Demystifying Sample Preparation for Headspace Analysis Using Direct Injection Mass Spectrometry
May 1st 2023Direct-injection mass spectrometry (DIMS) and gas chromatography (GC) approaches have some significant differences that are pertinent when analyzing volatile organic compounds (VOCs). We explain.
High-Throughput Analysis of Volatile Compounds in Air, Water, and Soil Using SIFT-MS
July 1st 2018For the BTEX compounds, detection limits in the single-digit parts-per-billion concentration range (by volume) are readily achievable within seconds using selected ion flow tube mass spectrometry (SIFT-MS), because sample analysis is achieved without chromatography, preconcentration, or drying.