Special Issues-05-01-2013

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Gas Chromatography with Soft Ionization Mass Spectrometry for the Characterization of Natural Products

Kazuhisa Mitsui;Nobukazu Higashi;Melissa Dunkle;Kikuo Sasamoto;Nobou Ochiai;Bart Tienpont;Frank David;Pat Sandra

May 1st 2013

Soft ionization MS using GC–APCI-MS and GC–SMB-MS offers complementary identification power for the characterization of natural products, as illustrated by the identification of alkanes, sterols, long chain alcohols, and derivatized polar compounds in tobacco leaf extracts described here.

Ambient Ionization MS Analysis of Swabs Used for Explosives Detection

Cécile Hubert;Xavier Machuron-Mandard;Jean-Claude Tabet

May 1st 2013

ArticleArticle

An analysis of the capabilities of direct analysis in real time (DART) and desorption electrospray ionization (DESI) sources for the analysis of contaminated fabrics

Screening by LC–MS-MS and Fast Chromatography: An Alternative Approach to Traditional Immunoassays?

Werner Bernhard;Thomas Wüthrich;Wolfgang Weinmann;Stefan Brand

May 1st 2013

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A new technique was developed based on liquid chromatography coupled with tandem mass spectrometry to analyze drugs that are not part of current immunoassay screening, specifically zolpidem, zopiclone, and zaleplone, or "z-drugs."

LC–HRMS Determination of Anticancer Drugs as Occupational Contaminants Applied to Photocatalytic Degradation of Molecules of Different Stability

Claudio Baiocchi;Paola Calza;Claudio Medana;Federica Dal Bello

May 1st 2013

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Here, degradation compounds similar to those formed in metabolic or environmental pathways were generated by adopting a photocatalytic process, quantified in environmental samples by liquid chromatography with multiple-stage mass spectrometry (LC–MSn) analysis using an orbital trap instrument with an electrospray interface, and then identified in indoor environments alongside parent compounds.